Leaders in cardiac clinical research

Our Heart Team comprised of experts in Cardiothoracic Surgery and Interventional Cardiology have together performed over 1,500 surgeries and transcatheter interventions treating mitral valve disease including some of the most complex and high-risk cases since 1985. The depth of our Heart Team's experience allows our program to offer clinical research opportunities for patients with heart disease. In partnership with HCA Healthcare Research Institute and Dallas Valve Institute at Medical City Heart Hospital, our program has the ability to be leading the advancement of technology and approaches to heart valve disease treatment.

The Dallas Valve Institute at Medical City Heart Hospital provides lifesaving heart and vascular care with seamless access to the entire network of Medical City Healthcare hospitals and specialists, leading edge treatments and technology, and groundbreaking clinical trials. For more information about participating in clinical trials, please contact the research office by calling (972) 940-8113.

Current clinical trials

CLASP IID/IIF study

Condition
Mitral Valve Regurgitation
What is Mitral Regurgitation?

Intervention
Transcatheter Mitral Valve Repair
Get Treatment for Mitral Regurgitation and Help Others Like You

Investigators
Bruce Bowers, MD
Todd Dewey, MD
Jake Chemmalakuzhy, MD
Sireesha Vasireddy, MD

Official Title: A prospective, multicenter, randomized, controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with degenerative mitral regurgitation (DMR) who have been determined to be at prohibitive risk for mitral valve surgery by the Heart Team, and in patients with functional mitral regurgitation (FMR) on guideline directed medical therapy (GDMT)

For more information about this study, call (972) 940-8113.

Aline Barzilla, Director of Research
Email Aline Barzilla

Brandon Prince, Sr. Research Coordinator
Email Brandon Prince

SUMMIT

Condition
Mitral Valve Regurgitation

Intervention
Transcatheter Mitral Valve Replacement
Introducing the SUMMIT Trial

Investigators
Bruce Bowers, MD
Todd Dewey, MD

Official Title: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

For more information about this study, call (972) 940-8113.

Aline Barzilla, Director of Research
Email Aline Barzilla

Brandon Prince, Sr. Research Coordinator
Email Brandon Prince

P3-AVIV

Condition
Failing Aortic Bioprosthetic Valve

Intervention
Transcatheter Valve Replacement

Investigators
Bruce Bowers, MD Todd Dewey, MD

Official Title: P3-AVIV is a Prospective, Single-arm, Multicenter Clinical Trial That Will Establish the Safety and Efficacy of SAPIEN 3 THV in Patients With a Failing Aortic Bioprosthetic Valve

For more information about this study, call (972) 940-8113 .

Aline Barzilla, Director of Research
Email Aline Barzilla

Brandon Prince, Sr. Research Coordinator
Email Brandon Prince